Recombinant or Urinary Human Chorionic Gonadotropin in Ovulation Induction?
نویسندگان
چکیده
منابع مشابه
Recombinant or urinary human chorionic gonadotropin in ovulation induction?
The onset of the spontaneous LH surge in women is relatively abrupt with concentrations doubling within 2 h to between 100 and 200 IU/l being sustained for 12–14 h over a mean duration of 50 h [1]. This mid-cycle surge, in addition to follicular rupture [2], promotes several periovulatory events including disruption of the oocyte– cumulus oophorus cell contact and induction of the resumption of...
متن کاملP-165: Comparison of Urinary and Recombinant Human Chorionic Gonadotropin during Ovulation Induction in Intrauterine Insemination Cycles
Background: Urinary human chorionic gonadotropin is the most widely used medicine for ovulation in ovarian stimulation cycles. Recently however, recombinant HCG has also become commercially available. This study presents compare the use of recombinant hCG with urinary hCG during controlled ovarian hyperstimulation and intra uterine insemination (COH-IUI ) cycles Materials and Methods: This is s...
متن کاملMonitoring of ovulation induction with human menopausal gonadotropin and human chorionic gonadotropin by ultrasonography : prevention of ovarian hyperstiumulation Syndrome
We monitored follicular development by ultrasonography on 40 anovulatory women on the day when we switched from HMG to HCG, and measured the maximum follicular diameter (mFD) and the sum total of follicular cross sectional area (FA) and examined the correlations of both mFD and FA with ovulation or OHSS. The ovulatory rate with mFD of more than 18mm was 100%. The correlation coefficients betwee...
متن کاملSingle‐dose pharmacokinetic study comparing the pharmacokinetics of recombinant human chorionic gonadotropin in healthy Japanese and Caucasian women and recombinant human chorionic gonadotropin and urinary human chorionic gonadotropin in healthy Japanese women
Purpose Recombinant hCG (r-hCG) was approved in Japan in 2016. As a prerequisite for a Phase III study in Japan related to this approval, the pharmacokinetic (PK) profile of r-hCG was investigated. Methods An open-label, partly randomized, single-center, single-dose, group-comparison, Phase I PK-bridging study was done that compared a single 250 μg dose of r-hCG with a single 5000 IU dose of ...
متن کاملPregnancy Rates with Recombinant versus Urinary Human Chorionic Gonadotropin in In Vitro Fertilization: An Observational Study
Randomized clinical trials (RCTs) demonstrated the equal efficacy of urinary human chorionic gonadotropin (uhCG) and recombinant hCG (rhCG) products in in vitro fertilisation (IVF). However, limitations inherent with RCTs necessitate the reinforcement of RCT results in real-life. We retrospectively analyzed pregnancies after treatment with rhCG and uhCG products (n = 391, and 96, resp.). We fou...
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ژورنال
عنوان ژورنال: The Journal of Obstetrics and Gynecology of India
سال: 2011
ISSN: 0971-9202,0975-6434
DOI: 10.1007/s13224-011-0114-8